Overview
PET Scan is a nuclear medicine imaging technique used to assess metabolic activity in the body.
Introduction / Historical Perspective
Positron Emission Tomography (PET) Scan is a medical imaging technique that uses radioactive tracers to visualize metabolic processes in the body. Developed in the 1970s, PET scans have become crucial in diagnosing and managing various diseases, especially cancer.
What is a PET scan?
A PET scan is a type of imaging test that uses a radioactive tracer (usually FDG – Fluorodeoxyglucose) to detect metabolic changes in the body, highlighting areas with high glucose uptake, like cancer cells.
Mechanism of PET Scan
- 1. Injection of FDG tracer
- 2. Uptake by cells (higher in cancer cells)
- 3. Emission of positrons, detected by scanner
- 4. Image creation showing metabolic activity
Indications for PET Scan
- Cancer diagnosis and staging (e.g., lung, breast, lymphoma)
- Monitoring treatment response
- Detecting recurrence
- Neurological disorders (e.g., Alzheimer's)
Contraindications for PET Scan
- Pregnancy/breastfeeding
- Uncontrolled diabetes (affects image quality)
- Allergy to tracer components
Interpretation of PET Scan Images
SUV (Standardized Uptake Value):
Measures the tracer uptake.
- High SUV often indicates malignancy
- Correlate with clinical history and other imaging
Correlations Between CT Scan, MRI Scan, and PET Scan
| Modality | Use Case |
|---|---|
|
PET Scan |
Metabolic activity |
|
CT Scan |
Structural info (anatomy) |
|
MRI Scan |
Soft tissue detail |
Test Details
Sensitivity
Specificity
False Positivity
False Negativity
Negative Predictive Value
Positive Predictive Value
Best Time for Postoperative PET Scan
Best Time for PET Scan After Radiotherapy
PET scans are valuable for assessing metabolic activity, aiding diagnosis, staging, and treatment monitoring, especially in oncology. Interpretation requires correlation with clinical context and other imaging.
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